You’re in luck… this is already done for the January 2025 version. The new quality setting is approximately equal to “visually lossless”, which means there is no loss of quality that the human eye is able to detect. Storing more data beyond that (i.e., 100%) is usually wasted disk space for a final export. See the announcement for the next version here:
Unfortunately, the computer world is full of geek talk that is confusing to people that don’t live in it. In this context, “High Profile” does not refer to High Quality. It’s actually written as “High” profile, meaning there are three popular profiles for H.264 encoders… baseline, main, and high (there are export presets for each). The difference between them is the mathematical tools that they’re allowed to use to make file sizes smaller. Baseline uses simple math functions that mobile and hardware devices can easily decode on weak battery power. High profile uses more complex math that needs a faster computer to decode, but the advanced math allows for smaller file sizes at the same quality level. (These days, of course, all systems are capable of playing all profiles since this codec has become 20+ years old and technology has improved drastically.) These preset names are not references to quality… they are references to computational complexity to get the requested quality.
However, to address the common request for highest quality without huge file sizes, the High profile has been updated to provide visually lossless quality, and it is now a one-click solution for high-quality future exports.
If you have a PowerPoint presentation and want the ultimate in small file sizes, also consider the “Slide Deck (H.264)” export preset. It was designed for that purpose, although in your case you may wish to improve its default audio settings.